PHILADELPHIA, Pa.--(BUSINESS WIRE)--Oct. 1, 1996--HEMISPHERx Biopharma, Inc. (NASDAQ:HEMX) announced today that it began shipment of Ampligen (R) to Rivex Biopharma, Inc. (Aurora, Ontario). Ampligen will be administered in Canada under the Emergency Drug Release Program, at the request of Canadian physicians. Ampligen may be used for treatment of patients suffering from Chronic Fatigue and Immune Dysfunction Syndrome (CFIDS), also known as Chronic Fatigue Syndrome (CFS), or Myalgic Encephalomyelitis (ME). It has also been found to have activity against HIV, Hepititis B, and in the treatment of Metastatic Renal Cell Cancer. CFIDS is a multisystem syndrome characterized by months of debilitating fatigue frequently associated with myalgia, headache, sore throat, low grade fever and tender lymph nodes. The medical community estimates that approximately 400,000 people suffer from CFIDS in the United States. The illness interferes with every-day simple tasks such as walking, driving a car, and remembering appointments, and it causes some patients to become bed ridden. In the United States, additional information about Chronic Fatigue Syndrome can be obtained from the National CFIDS Association by calling 1-800-442-3437. Ampligen is an antiviral and immune modulatory drug under the nucleic acid class of drugs (NAs). Nas are drugs designed to mimic the body's own digitized informational molecules (called DNA and RNA) which, in some laboratory and animal studies, reprogram certain diseased cells to enhance their intrinsic disease fighting capabilities. Over the last several years, HEMISPHERx has conducted clinical and laboratory investigations of NAs in more than twenty major academic research institutions in the United States. Abroad, Ampligen is currently used in a clinical program with cost recovery in Belgium in academic partnership with Kenny De Meirleir, M.D., Ph.D, from the University of Brussels Akademisch Ziekenhuis. An update on the Belgium program will be presented in San Francisco on October 14th at the 1996 American Association for Chronic Fatigue Syndrome (AACFS) Research and Clinical Conference. HEMISPHERx is a pharmaceutical company engaged in the manufacture and global clinical development of drugs entities in the NA class for chronic viral diseases and disorders of the immune system. To date, HEMISPHERx and its subsidiaries have received over 200 patents internationally to protect its proprietary position in NA and related drug technologies. CONTACT: HEMISPHERx Biopharma, Inc. R. Douglas Hulse, COO 215/988-0080 or VMW, Inc. Vicki Miles Weiner, 212/605-3140 VMWeiner@aol.com KEYWORD: PENNSYLVANIA INDUSTRY KEYWORD: PHARMACEUTICAL BIOTECHNOLOGY MEDICINE PRODUCT BW1276 OCT 01,1996